Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m

The research objective is to design intranasal (IN) brain targeted CLZ-loaded polymeric nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct equilibrium method was used to prepare CLZ-PNMS using two hydrophobic poloxamines; Tetronic(®) 904 (T904) and Tetronic(®)...

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Detalles Bibliográficos
Autores principales: Sayed, Sinar, Elsharkawy, Fatma M., Amin, Maha M., Shamsel-Din, Hesham A., Ibrahim, Ahmed B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288143/
https://www.ncbi.nlm.nih.gov/pubmed/34266360
http://dx.doi.org/10.1080/10717544.2021.1951895

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288143/
https://www.ncbi.nlm.nih.gov/pubmed/34266360
http://dx.doi.org/10.1080/10717544.2021.1951895

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