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Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential

Telomerase-based therapeutic cancer vaccines (TCVs) have been under clinical investigation for the past two decades. Despite past failures, TCVs have gained renewed enthusiasm for their potential to improve the efficacy of checkpoint inhibition. Telomerase stands as an attractive target for TCVs due...

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Detalles Bibliográficos
Autores principales: Ellingsen, Espen Basmo, Mangsbo, Sara M., Hovig, Eivind, Gaudernack, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288190/
https://www.ncbi.nlm.nih.gov/pubmed/34290704
http://dx.doi.org/10.3389/fimmu.2021.682492