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A single-cell transcriptomic atlas of primate pancreatic islet aging

Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes. Endocrine cells age heterogeneously, complicating the efforts to unravel the molecular drivers underlying endocrine aging. To overcome these obstacles, we undertook single-cell RNA sequencing...

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Detalles Bibliográficos
Autores principales: Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Izpisua Belmonte, Juan Carlos, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, Guang-Hui, Tang, Fuchou, Qu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288398/
https://www.ncbi.nlm.nih.gov/pubmed/34691567
http://dx.doi.org/10.1093/nsr/nwaa127