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A single-cell transcriptomic atlas of primate pancreatic islet aging
Aging-related degeneration of pancreatic islet cells contributes to impaired glucose tolerance and diabetes. Endocrine cells age heterogeneously, complicating the efforts to unravel the molecular drivers underlying endocrine aging. To overcome these obstacles, we undertook single-cell RNA sequencing...
Autores principales: | Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Izpisua Belmonte, Juan Carlos, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, Guang-Hui, Tang, Fuchou, Qu, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288398/ https://www.ncbi.nlm.nih.gov/pubmed/34691567 http://dx.doi.org/10.1093/nsr/nwaa127 |
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