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A virtual sequencer reveals the dephasing patterns in error-correction code DNA sequencing

An error-correction code (ECC) sequencing approach has recently been reported to effectively reduce sequencing errors by interrogating a DNA fragment with three orthogonal degenerate sequencing-by-synthesis (SBS) reactions. However, similar to other non-single-molecule SBS methods, the reaction will...

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Detalles Bibliográficos
Autores principales: Zhou, Wenxiong, Kang, Li, Duan, Haifeng, Qiao, Shuo, Tao, Louis, Chen, Zitian, Huang, Yanyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288425/
https://www.ncbi.nlm.nih.gov/pubmed/34691637
http://dx.doi.org/10.1093/nsr/nwaa227