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Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases

Factor H (FH)–related proteins are a group of partly characterized complement proteins thought to promote complement activation by competing with FH in binding to surface-bound C3b. Among them, FH-related protein 1 (FHR-1) is remarkable because of its association with atypical hemolytic uremic syndr...

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Detalles Bibliográficos
Autores principales: Martin Merinero, Héctor, Subías, Marta, Pereda, Amaia, Gómez-Rubio, Elena, Juana Lopez, Lucia, Fernandez, Constantino, Goicoechea de Jorge, Elena, Martin-Santamaria, Sonsoles, Cañada, Francisco Javier, Rodríguez de Córdoba, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288665/
https://www.ncbi.nlm.nih.gov/pubmed/33651882
http://dx.doi.org/10.1182/blood.2020010069