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Molecular bases for the association of FHR-1 with atypical hemolytic uremic syndrome and other diseases
Factor H (FH)–related proteins are a group of partly characterized complement proteins thought to promote complement activation by competing with FH in binding to surface-bound C3b. Among them, FH-related protein 1 (FHR-1) is remarkable because of its association with atypical hemolytic uremic syndr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8288665/ https://www.ncbi.nlm.nih.gov/pubmed/33651882 http://dx.doi.org/10.1182/blood.2020010069 |