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The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons

During development, signal-regulated transcription factors (TFs) act as basal repressors and upon signalling through morphogens or cell-to-cell signalling shift to activators, mediating precise and transient responses. Conversely, at the final steps of neuron specification, terminal selector TFs dir...

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Detalles Bibliográficos
Autores principales: Maicas, Miren, Jimeno-Martín, Ángela, Millán-Trejo, Andrea, Alkema, Mark J., Flames, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289040/
https://www.ncbi.nlm.nih.gov/pubmed/34232959
http://dx.doi.org/10.1371/journal.pbio.3001334