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The transcription factor LAG-1/CSL plays a Notch-independent role in controlling terminal differentiation, fate maintenance, and plasticity of serotonergic chemosensory neurons
During development, signal-regulated transcription factors (TFs) act as basal repressors and upon signalling through morphogens or cell-to-cell signalling shift to activators, mediating precise and transient responses. Conversely, at the final steps of neuron specification, terminal selector TFs dir...
Autores principales: | Maicas, Miren, Jimeno-Martín, Ángela, Millán-Trejo, Andrea, Alkema, Mark J., Flames, Nuria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289040/ https://www.ncbi.nlm.nih.gov/pubmed/34232959 http://dx.doi.org/10.1371/journal.pbio.3001334 |
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