Germinal Center T follicular helper (GC-Tfh) cell impairment in chronic HIV infection involves c-Maf signaling

We have recently demonstrated that the function of T follicular helper (Tfh) cells from lymph nodes (LN) of HIV-infected individuals is impaired. We found that these cells were unable to provide proper help to germinal center (GC)-B cells, as observed by altered and inefficient anti-HIV antibody res...

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Detalles Bibliográficos
Autores principales: Chakhtoura, Marita, Fang, Mike, Cubas, Rafael, O’Connor, Margaret H., Nichols, Carmen N., Richardson, Brian, Talla, Aarthi, Moir, Susan, Cameron, Mark J., Tardif, Virginie, Haddad, Elias K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289045/
https://www.ncbi.nlm.nih.gov/pubmed/34280251
http://dx.doi.org/10.1371/journal.ppat.1009732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289045/
https://www.ncbi.nlm.nih.gov/pubmed/34280251
http://dx.doi.org/10.1371/journal.ppat.1009732

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