Functional requirement of terminal inverted repeats for efficient ProtoRAG activity reveals the early evolution of V(D)J recombination

The discovery of ProtoRAG in amphioxus indicated that vertebrate RAG recombinases originated from an ancient transposon. However, the sequences of ProtoRAG terminal inverted repeats (TIRs) were obviously dissimilar to the consensus sequence of mouse 12/23RSS and recombination mediated by ProtoRAG or...

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Detalles Bibliográficos
Autores principales: Tao, Xin, Yuan, Shaochun, Chen, Fan, Gao, Xiaoman, Wang, Xinli, Yu, Wenjuan, Liu, Song, Huang, Ziwen, Chen, Shangwu, Xu, Anlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289069/
https://www.ncbi.nlm.nih.gov/pubmed/34692056
http://dx.doi.org/10.1093/nsr/nwz179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289069/
https://www.ncbi.nlm.nih.gov/pubmed/34692056
http://dx.doi.org/10.1093/nsr/nwz179

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