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Surveying brain tumor heterogeneity by single-cell RNA-sequencing of multi-sector biopsies

Brain tumors are among the most challenging human tumors for which the mechanisms driving progression and heterogeneity remain poorly understood. We combined single-cell RNA-seq with multi-sector biopsies to sample and analyze single-cell expression profiles of gliomas from 13 Chinese patients. Afte...

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Detalles Bibliográficos
Autores principales: Yu, Kai, Hu, Yuqiong, Wu, Fan, Guo, Qiufang, Qian, Zenghui, Hu, Waner, Chen, Jing, Wang, Kuanyu, Fan, Xiaoying, Wu, Xinglong, Rasko, John EJ, Fan, Xiaolong, Iavarone, Antonio, Jiang, Tao, Tang, Fuchou, Su, Xiao-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289159/
https://www.ncbi.nlm.nih.gov/pubmed/34692159
http://dx.doi.org/10.1093/nsr/nwaa099