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Tritylamine as an Ammonia Surrogate in the Ugi Reaction Provides Access to Unprecedented 5-Sulfamido Oxazoles Using Burgess-type Reagents
[Image: see text] Starting from a wide range of α-acylamino amide substructures synthesized using tritylamine as an ammonia surrogate in the Ugi reaction, Burgess-type reagents enable cyclodehydration and afford unprecedented oxazole scaffolds with four points of diversity, including a sulfamide moi...
Autores principales: | Bhela, Irene Preet, Serafini, Marta, Del Grosso, Erika, Tron, Gian Cesare, Pirali, Tracey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289289/ https://www.ncbi.nlm.nih.gov/pubmed/33913716 http://dx.doi.org/10.1021/acs.orglett.1c01002 |
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