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The Role of Cyclodextrins against Interface-Induced Denaturation in Pharmaceutical Formulations: A Molecular Dynamics Approach

[Image: see text] Protein-based pharmaceutical products are subject to a variety of environmental stressors, during both production and shelf-life. In order to preserve their structure, and, therefore, functionality, it is necessary to use excipients as stabilizing agents. Among the eligible stabili...

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Detalles Bibliográficos
Autores principales: Rospiccio, Marcello, Arsiccio, Andrea, Winter, Gerhard, Pisano, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289300/
https://www.ncbi.nlm.nih.gov/pubmed/33999634
http://dx.doi.org/10.1021/acs.molpharmaceut.1c00135