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Pd-Catalyzed Cascade Reactions of Aziridines: One-Step Access to Complex Tetracyclic Amines

[Image: see text] The combination of palladium catalysis and thermal cycloaddition is shown to transform tricyclic aziridines into complex, stereodefined tetracyclic products in a single step. This highly unusual cascade process involves a diverted Tsuji–Trost sequence leading to a surprisingly faci...

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Detalles Bibliográficos
Autores principales: Knowles, Jonathan P., Steeds, Hannah G., Schwarz, Maria, Latter, Francesca, Booker-Milburn, Kevin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289308/
https://www.ncbi.nlm.nih.gov/pubmed/34132553
http://dx.doi.org/10.1021/acs.orglett.1c01403