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Quantification of P-Glycoprotein in the Gastrointestinal Tract of Humans and Rodents: Methodology, Gut Region, Sex, and Species Matter

[Image: see text] Intestinal efflux transporters affect the gastrointestinal processing of many drugs but further data on their intestinal expression levels are required. Relative mRNA expression and relative and absolute protein expression data of transporters are commonly measured by real-time pol...

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Detalles Bibliográficos
Autores principales: Mai, Yang, Dou, Liu, Yao, Zhicheng, Madla, Christine M., Gavins, Francesca K. H., Taherali, Farhan, Yin, Heyue, Orlu, Mine, Murdan, Sudaxshina, Basit, Abdul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289313/
https://www.ncbi.nlm.nih.gov/pubmed/33886332
http://dx.doi.org/10.1021/acs.molpharmaceut.0c00574