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Computer Aided Design of Solvent Blends for Hybrid Cooling and Antisolvent Crystallization of Active Pharmaceutical Ingredients

[Image: see text] Choosing a solvent and an antisolvent for a new crystallization process is challenging due to the sheer number of possible solvent mixtures and the impact of solvent composition and crystallization temperature on process performance. To facilitate this choice, we present a general...

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Detalles Bibliográficos
Autores principales: Watson, Oliver L., Jonuzaj, Suela, McGinty, John, Sefcik, Jan, Galindo, Amparo, Jackson, George, Adjiman, Claire S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289336/
https://www.ncbi.nlm.nih.gov/pubmed/34295139
http://dx.doi.org/10.1021/acs.oprd.0c00516