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A Novel Integrated Workflow for Isolation Solvent Selection Using Prediction and Modeling

[Image: see text] A predictive tool was developed to aid process design and to rationally select optimal solvents for isolation of active pharmaceutical ingredients. The objective was to minimize the experimental work required to design a purification process by (i) starting from a rationally select...

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Detalles Bibliográficos
Autores principales: Ottoboni, Sara, Wareham, Bruce, Vassileiou, Antony, Robertson, Murray, Brown, Cameron J., Johnston, Blair, Price, Chris J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289338/
https://www.ncbi.nlm.nih.gov/pubmed/34295140
http://dx.doi.org/10.1021/acs.oprd.0c00532