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Tissue Kallikrein Exacerbating Sepsis-Induced Endothelial Hyperpermeability is Highly Predictive of Severity and Mortality in Sepsis

AIM: Sepsis, an acute, life-threatening dysregulated response to infection, affects practically all aspects of endothelial function. Tissue kallikrein (TK) is a key enzyme in the kallikrein–kinin system (KKS) which has been implicated in endothelial permeability. Thus, we aimed to establish a potent...

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Detalles Bibliográficos
Autores principales: Ran, Xiao, Zhang, Qin, Li, Shaoping, Yu, Zhen, Wan, Li, Wu, Bin, Wu, Rongxue, Li, Shusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289368/
https://www.ncbi.nlm.nih.gov/pubmed/34290517
http://dx.doi.org/10.2147/JIR.S317874