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Tissue Kallikrein Exacerbating Sepsis-Induced Endothelial Hyperpermeability is Highly Predictive of Severity and Mortality in Sepsis
AIM: Sepsis, an acute, life-threatening dysregulated response to infection, affects practically all aspects of endothelial function. Tissue kallikrein (TK) is a key enzyme in the kallikrein–kinin system (KKS) which has been implicated in endothelial permeability. Thus, we aimed to establish a potent...
Autores principales: | Ran, Xiao, Zhang, Qin, Li, Shaoping, Yu, Zhen, Wan, Li, Wu, Bin, Wu, Rongxue, Li, Shusheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289368/ https://www.ncbi.nlm.nih.gov/pubmed/34290517 http://dx.doi.org/10.2147/JIR.S317874 |
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