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The solubility product extends the buffering concept to heterotypic biomolecular condensates

Biomolecular condensates are formed by liquid-liquid phase separation (LLPS) of multivalent molecules. LLPS from a single ("homotypic") constituent is governed by buffering: above a threshold, free monomer concentration is clamped, with all added molecules entering the condensed phase. How...

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Detalles Bibliográficos
Autores principales: Chattaraj, Aniruddha, Blinov, Michael L, Loew, Leslie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289413/
https://www.ncbi.nlm.nih.gov/pubmed/34236318
http://dx.doi.org/10.7554/eLife.67176