Effect of Concomitant Benzodiazepine Use on Efficacy and Safety of Esketamine Nasal Spray in Patients with Major Depressive Disorder and Acute Suicidal Ideation or Behavior: Pooled Randomized, Controlled Trials

PURPOSE: The impact of benzodiazepines on the efficacy and safety of esketamine as a rapid-acting antidepressant remains unclear. MATERIALS AND METHODS: Data from two identically designed, randomized double-blind studies were pooled and analyzed on a post-hoc basis. In both studies, adults with majo...

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Detalles Bibliográficos
Autores principales: Diekamp, Bettina, Borentain, Stephane, Fu, Dong-Jing, Murray, Robert, Heerlein, Kristin, Zhang, Qiaoyi, Schüle, Cornelius, Mathews, Maju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289440/
https://www.ncbi.nlm.nih.gov/pubmed/34290505
http://dx.doi.org/10.2147/NDT.S314874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289440/
https://www.ncbi.nlm.nih.gov/pubmed/34290505
http://dx.doi.org/10.2147/NDT.S314874

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