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Mitochondrial ATP-Sensitive K+ Channel Opening Increased the Airway Smooth Muscle Cell Proliferation by Activating the PI3K/AKT Signaling Pathway in a Rat Model of Asthma

Abnormal proliferation of airway smooth muscle cells (ASMCs) leads to airway remodeling and the development of asthma. This study aimed to assess whether mitochondrial ATP-sensitive K+ (mitoK(ATP)) channels regulated the proliferation of ASMCs by regulating the phosphoinositide 3-kinase/protein kina...

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Detalles Bibliográficos
Autores principales: Gao, Min, Sun, Qinran, Liu, Qingfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289566/
https://www.ncbi.nlm.nih.gov/pubmed/34336047
http://dx.doi.org/10.1155/2021/8899878