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Trehalose Augments Neuron Survival and Improves Recovery from Spinal Cord Injury via mTOR-Independent Activation of Autophagy

Spinal cord injury (SCI) is a major cause of irreversible nerve injury and leads to serious tissue loss and neurological dysfunction. Thorough investigation of cellular mechanisms, such as autophagy, is crucial for developing novel and effective therapeutics. We administered trehalose, an mTOR-indep...

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Detalles Bibliográficos
Autores principales: Zhou, Kailiang, Chen, Huanwen, Xu, Huazi, Jia, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289614/
https://www.ncbi.nlm.nih.gov/pubmed/34336117
http://dx.doi.org/10.1155/2021/8898996