Development of safe and highly protective live-attenuated SARS-CoV-2 vaccine candidates by genome recoding

Safe and effective vaccines are urgently needed to stop the pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We construct a series of live attenuated vaccine candidates by large-scale recoding of the SARS-CoV-2 genome and assess their safety and efficacy in Syrian ham...

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Detalles Bibliográficos
Autores principales: Trimpert, Jakob, Dietert, Kristina, Firsching, Theresa C., Ebert, Nadine, Thi Nhu Thao, Tran, Vladimirova, Daria, Kaufer, Susanne, Labroussaa, Fabien, Abdelgawad, Azza, Conradie, Andelé, Höfler, Thomas, Adler, Julia M., Bertzbach, Luca D., Jores, Joerg, Gruber, Achim D., Thiel, Volker, Osterrieder, Nikolaus, Kunec, Dusan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289629/
https://www.ncbi.nlm.nih.gov/pubmed/34320400
http://dx.doi.org/10.1016/j.celrep.2021.109493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289629/
https://www.ncbi.nlm.nih.gov/pubmed/34320400
http://dx.doi.org/10.1016/j.celrep.2021.109493

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