L-type channel inactivation balances the increased peak calcium current due to absence of Rad in cardiomyocytes

The L-type Ca(2+) channel (LTCC) provides trigger calcium to initiate cardiac contraction in a graded fashion that is regulated by L-type calcium current (I(Ca,L)) amplitude and kinetics. Inactivation of LTCC is controlled to fine-tune calcium flux and is governed by voltage-dependent inactivation (...

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Detalles Bibliográficos
Autores principales: Ahern, Brooke M., Sebastian, Andrea, Levitan, Bryana M., Goh, Jensen, Andres, Douglas A., Satin, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289690/
https://www.ncbi.nlm.nih.gov/pubmed/34269819
http://dx.doi.org/10.1085/jgp.202012854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289690/
https://www.ncbi.nlm.nih.gov/pubmed/34269819
http://dx.doi.org/10.1085/jgp.202012854

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