Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication

Coronaviruses rely on host membranes for entry, establishment of replication centers, and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as antivirals and are actively being pursued as treatments for other conditions. Here, we test...

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Detalles Bibliográficos
Autores principales: Williams, Caroline G., Jureka, Alexander S., Silvas, Jesus A., Nicolini, Anthony M., Chvatal, Stacie A., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Basler, Christopher F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289695/
https://www.ncbi.nlm.nih.gov/pubmed/34320401
http://dx.doi.org/10.1016/j.celrep.2021.109479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289695/
https://www.ncbi.nlm.nih.gov/pubmed/34320401
http://dx.doi.org/10.1016/j.celrep.2021.109479

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