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Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication
Coronaviruses rely on host membranes for entry, establishment of replication centers, and egress. Compounds targeting cellular membrane biology and lipid biosynthetic pathways have previously shown promise as antivirals and are actively being pursued as treatments for other conditions. Here, we test...
Autores principales: | Williams, Caroline G., Jureka, Alexander S., Silvas, Jesus A., Nicolini, Anthony M., Chvatal, Stacie A., Carlson-Stevermer, Jared, Oki, Jennifer, Holden, Kevin, Basler, Christopher F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289695/ https://www.ncbi.nlm.nih.gov/pubmed/34320401 http://dx.doi.org/10.1016/j.celrep.2021.109479 |
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