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A non-RBM targeted RBD specific antibody neutralizes SARS-CoV-2 inducing S1 shedding

Potent neutralizing antibodies (Abs) have been proven with therapeutic efficacy for the intervention against SARS-CoV-2. Majority of these Abs function by directly interfering with the virus entry to host cells. Here, we identified a receptor binding domain (RBD) specific monoclonal Ab (mAb) 82A6 wi...

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Detalles Bibliográficos
Autores principales: Long, Yingyi, Song, Shuyi, Luo, Feiyang, Han, Xiaojian, Hu, Chao, Wang, Yingming, Li, Shenglong, Wang, Wang, Zhang, Huajun, Zhang, Bo, Li, Tingting, Jin, Aishun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289697/
https://www.ncbi.nlm.nih.gov/pubmed/34325131
http://dx.doi.org/10.1016/j.bbrc.2021.07.062