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Targeted base editing in the plastid genome of Arabidopsis thaliana

Bacterial cytidine deaminase fused to the DNA binding domains of transcription activator-like effector nucleases was recently reported to transiently substitute a targeted C to a T in mitochondrial DNA of mammalian cultured cells(1). We applied this system to targeted base editing in the Arabidopsis...

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Detalles Bibliográficos
Autores principales: Nakazato, Issei, Okuno, Miki, Yamamoto, Hiroshi, Tamura, Yoshiko, Itoh, Takehiko, Shikanai, Toshiharu, Takanashi, Hideki, Tsutsumi, Nobuhiro, Arimura, Shin-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289735/
https://www.ncbi.nlm.nih.gov/pubmed/34211131
http://dx.doi.org/10.1038/s41477-021-00954-6