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Trophoblast glycoprotein is a marker for efficient sorting of ventral mesencephalic dopaminergic precursors derived from human pluripotent stem cells

Successful cell therapy for Parkinson’s disease (PD) requires large numbers of homogeneous ventral mesencephalic dopaminergic (vmDA) precursors. Enrichment of vmDA precursors via cell sorting is required to ensure high safety and efficacy of the cell therapy. Here, using LMX1A-eGFP knock-in reporter...

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Detalles Bibliográficos
Autores principales: Yoo, Jeong-Eun, Lee, Dongjin R., Park, Sanghyun, Shin, Hye-Rim, Lee, Kun Gu, Kim, Dae-Sung, Jo, Mi-Young, Eom, Jang-Hyeon, Cho, Myung Soo, Hwang, Dong-Youn, Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289854/
https://www.ncbi.nlm.nih.gov/pubmed/34282148
http://dx.doi.org/10.1038/s41531-021-00204-8