M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway

Hepatocellular carcinoma (HCC) is a common malignancy. CD8(+) T cell-mediated immune response is critical for the inhibition of HCC progression. M2 macrophages participate in HCC progression. This study set out to investigate the effect of M2 macrophage-derived extracellular vesicles (EVs) on CD8(+)...

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Detalles Bibliográficos
Autores principales: Pu, Jian, Xu, Zuoming, Nian, Jiahui, Fang, Quan, Yang, Meng, Huang, Youguan, Li, Wenchuan, Ge, Bin, Wang, Jianchu, Wei, Huamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289864/
https://www.ncbi.nlm.nih.gov/pubmed/34282135
http://dx.doi.org/10.1038/s41420-021-00556-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289864/
https://www.ncbi.nlm.nih.gov/pubmed/34282135
http://dx.doi.org/10.1038/s41420-021-00556-3

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