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Myofibroblast transcriptome indicates SFRP2(hi) fibroblast progenitors in systemic sclerosis skin
Skin and lung fibrosis in systemic sclerosis (SSc) is driven by myofibroblasts, alpha-smooth muscle actin expressing cells. The number of myofibroblasts in SSc skin correlates with the modified Rodnan skin score, the most widely used clinical measure of skin disease severity. Murine fibrosis models...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289865/ https://www.ncbi.nlm.nih.gov/pubmed/34282151 http://dx.doi.org/10.1038/s41467-021-24607-6 |