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Myofibroblast transcriptome indicates SFRP2(hi) fibroblast progenitors in systemic sclerosis skin

Skin and lung fibrosis in systemic sclerosis (SSc) is driven by myofibroblasts, alpha-smooth muscle actin expressing cells. The number of myofibroblasts in SSc skin correlates with the modified Rodnan skin score, the most widely used clinical measure of skin disease severity. Murine fibrosis models...

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Detalles Bibliográficos
Autores principales: Tabib, Tracy, Huang, Mengqi, Morse, Nina, Papazoglou, Anna, Behera, Rithika, Jia, Minxue, Bulik, Melissa, Monier, Daisy E., Benos, Panayiotis V., Chen, Wei, Domsic, Robyn, Lafyatis, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289865/
https://www.ncbi.nlm.nih.gov/pubmed/34282151
http://dx.doi.org/10.1038/s41467-021-24607-6