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Species-specific gamete recognition initiates fusion-driving trimer formation by conserved fusogen HAP2
Recognition and fusion between gametes during fertilization is an ancient process. Protein HAP2, recognized as the primordial eukaryotic gamete fusogen, is a structural homolog of viral class II fusion proteins. The mechanisms that regulate HAP2 function, and whether virus-fusion-like conformational...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289870/ https://www.ncbi.nlm.nih.gov/pubmed/34282138 http://dx.doi.org/10.1038/s41467-021-24613-8 |