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Species-specific gamete recognition initiates fusion-driving trimer formation by conserved fusogen HAP2

Recognition and fusion between gametes during fertilization is an ancient process. Protein HAP2, recognized as the primordial eukaryotic gamete fusogen, is a structural homolog of viral class II fusion proteins. The mechanisms that regulate HAP2 function, and whether virus-fusion-like conformational...

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Detalles Bibliográficos
Autores principales: Zhang, Jun, Pinello, Jennifer F., Fernández, Ignacio, Baquero, Eduard, Fedry, Juliette, Rey, Félix A., Snell, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289870/
https://www.ncbi.nlm.nih.gov/pubmed/34282138
http://dx.doi.org/10.1038/s41467-021-24613-8