Insulin protects acinar cells during pancreatitis by preserving glycolytic ATP supply to calcium pumps

Acute pancreatitis (AP) is serious inflammatory disease of the pancreas. Accumulating evidence links diabetes with severity of AP, suggesting that endogenous insulin may be protective. We investigated this putative protective effect of insulin during cellular and in vivo models of AP in diabetic mic...

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Detalles Bibliográficos
Autores principales: Bruce, Jason I. E., Sánchez-Alvarez, Rosa, Sans, Maria Dolors, Sugden, Sarah A., Qi, Nathan, James, Andrew D., Williams, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289871/
https://www.ncbi.nlm.nih.gov/pubmed/34282152
http://dx.doi.org/10.1038/s41467-021-24506-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8289871/
https://www.ncbi.nlm.nih.gov/pubmed/34282152
http://dx.doi.org/10.1038/s41467-021-24506-w

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