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Meta-regression of randomized control trials with antithrombotics: weak correlation between net clinical benefit and all cause-mortality
This study aimed to explore the validity of the use of the net clinical benefit (NCB), i.e. the sum of major bleeding and thrombotic events, as a potential surrogate for all-cause mortality in clinical trials assessing antithrombotics. Published randomized controlled trials testing anticoagulants in...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290002/ https://www.ncbi.nlm.nih.gov/pubmed/34282198 http://dx.doi.org/10.1038/s41598-021-94160-1 |