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Impaired SNF2L Chromatin Remodeling Prolongs Accessibility at Promoters Enriched for Fos/Jun Binding Sites and Delays Granule Neuron Differentiation

Chromatin remodeling proteins utilize the energy from ATP hydrolysis to mobilize nucleosomes often creating accessibility for transcription factors within gene regulatory elements. Aberrant chromatin remodeling has diverse effects on neuroprogenitor homeostasis altering progenitor competence, prolif...

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Detalles Bibliográficos
Autores principales: Goodwin, Laura R., Zapata, Gerardo, Timpano, Sara, Marenger, Jacob, Picketts, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290069/
https://www.ncbi.nlm.nih.gov/pubmed/34295220
http://dx.doi.org/10.3389/fnmol.2021.680280