IRE1α Expedites the Progression of Castration-Resistant Prostate Cancers via the Positive Feedback Loop of IRE1α/IL-6/AR

Castration-resistant prostate cancer (CRPC) is the lethal form of prostate cancer (PCa), and the underlying molecular mechanism has not been fully elucidated. Inositol requiring enzyme 1 alpha (IRE1α), a key regulator of unfolded protein response (UPR), is intimately associated with PCa progression....

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Detalles Bibliográficos
Autores principales: Yang, Fan, Yuan, Chong, Wu, Dan, Zhang, Jing, Zhou, Xingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290131/
https://www.ncbi.nlm.nih.gov/pubmed/34295814
http://dx.doi.org/10.3389/fonc.2021.671141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290131/
https://www.ncbi.nlm.nih.gov/pubmed/34295814
http://dx.doi.org/10.3389/fonc.2021.671141

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