Implementation and implications for polygenic risk scores in healthcare

Increasing amounts of genetic data have led to the development of polygenic risk scores (PRSs) for a variety of diseases. These scores, built from the summary statistics of genome-wide association studies (GWASs), are able to stratify individuals based on their genetic risk of developing various com...

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Detalles Bibliográficos
Autores principales: Slunecka, John L., van der Zee, Matthijs D., Beck, Jeffrey J., Johnson, Brandon N., Finnicum, Casey T., Pool, René, Hottenga, Jouke-Jan, de Geus, Eco J. C., Ehli, Erik A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290135/
https://www.ncbi.nlm.nih.gov/pubmed/34284826
http://dx.doi.org/10.1186/s40246-021-00339-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290135/
https://www.ncbi.nlm.nih.gov/pubmed/34284826
http://dx.doi.org/10.1186/s40246-021-00339-y

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