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Pharmacological Inactivation of CatSper Blocks Sperm Fertilizing Ability Independently of the Capacitation Status of the Cells: Implications for Non-hormonal Contraception
Cation channel of sperm (CatSper), the main sperm-specific Ca(2+) channel, plays a key role in mammalian fertilization, and it is essential for male fertility, becoming an attractive target for contraception. Based on this, in the present work, we investigated the effects of CatSper inactivation on...
Autores principales: | Curci, Ludmila, Carvajal, Guillermo, Sulzyk, Valeria, Gonzalez, Soledad Natalia, Cuasnicú, Patricia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290173/ https://www.ncbi.nlm.nih.gov/pubmed/34295893 http://dx.doi.org/10.3389/fcell.2021.686461 |
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