ADME gene polymorphisms do not influence the pharmacokinetics of docetaxel: Results from a population pharmacokinetic study in Indian cancer patients

BACKGROUND: Pharmacokinetics (PK) of docetaxel is characterized by high inter‐individual variability (IIV). While covariate models that explain the PK variability of docetaxel exist, not much is known about the effects of genetic variations on docetaxel disposition. METHODS: Fifty patients with head...

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Detalles Bibliográficos
Autores principales: Patil, Anand, Shriyan, Bharati, Mehta, Parsshava, Patil, Mrudula, Gurjar, Murari, Nookala, Manjunath, Patil, Vijay, Joshi, Amit, Noronha, Vanita, Prabhash, Kumar, Gota, Vikram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Cancer Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290241/
https://www.ncbi.nlm.nih.gov/pubmed/34156160
http://dx.doi.org/10.1002/cam4.4026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290241/
https://www.ncbi.nlm.nih.gov/pubmed/34156160
http://dx.doi.org/10.1002/cam4.4026

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