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Next‐generation sequencing of tissue and circulating tumor DNA: Resistance mechanisms to EGFR targeted therapy in a cohort of patients with advanced non‐small cell lung cancer

BACKGROUND: Epidermal growth factor receptor‐tyrosine kinase inhibitor (EGFR‐TKI) has been considered as an effective treatment in epidermal growth factor receptor‐mutant (EGFR‐mutant) advanced non‐small cell lung cancer (NSCLC). However, most patients develop acquired resistance eventually. Here, w...

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Detalles Bibliográficos
Autores principales: Zhang, Yujun, Xiong, Liwen, Xie, Fangfang, Zheng, Xiaoxuan, Li, Ying, Zhu, Lei, Sun, Jiayuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290257/
https://www.ncbi.nlm.nih.gov/pubmed/34173341
http://dx.doi.org/10.1002/cam4.3948