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Topologically Associating Domains and Regulatory Landscapes in Development, Evolution and Disease

Animal genomes are folded in topologically associating domains (TADs) that have been linked to the regulation of the genes they contain by constraining regulatory interactions between cis-regulatory elements and promoters. Therefore, TADs are proposed as structural scaffolds for the establishment of...

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Detalles Bibliográficos
Autores principales: Tena, Juan J., Santos-Pereira, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290416/
https://www.ncbi.nlm.nih.gov/pubmed/34295901
http://dx.doi.org/10.3389/fcell.2021.702787