Application of TGF-β1, TIMP-1 and TIMP-2 small interfering RNAs can alleviate CCl(4)-induced hepatic fibrosis in rats by rebalancing Th1/Th2 cytokines

The present study aimed to investigate the effects of TGF-β1, tissue inhibitor of metalloproteinase (TIMP)-1 small interfering (si)RNA and TIMP-2 siRNA on hepatic fibrosis in rats and explore the T helper (Th)1/Th2 balance. Moreover, IFN-γ, IL-4 and IL-13 are the main cytokines associated with Th1/T...

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Detalles Bibliográficos
Autores principales: Xue, Ying, Qian, Keli, Sun, Yinchun, Xiao, Lang, Shi, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290469/
https://www.ncbi.nlm.nih.gov/pubmed/34335905
http://dx.doi.org/10.3892/etm.2021.10395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290469/
https://www.ncbi.nlm.nih.gov/pubmed/34335905
http://dx.doi.org/10.3892/etm.2021.10395

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