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TIMP3 attenuates cerebral ischemia/reperfusion-induced apoptosis and oxidative stress in neurocytes by regulating the AKT pathway

Ischemic stroke seriously threatens human health and creates a large social burden. The present study investigated whether tissue inhibitor of metalloproteinases-3 (TIMP3) prevented cerebral ischemia/reperfusion (I/R), with the aim to explore the underlying mechanism. A transient middle cerebral art...

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Detalles Bibliográficos
Autores principales: Meng, Linglei, Zhang, Yongting, Li, Demao, Shang, Xinfang, Hao, Xuejia, Chen, Xin, Gao, Fengxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290470/
https://www.ncbi.nlm.nih.gov/pubmed/34335915
http://dx.doi.org/10.3892/etm.2021.10405