Histone deacetylase inhibitor panobinostat induces antitumor activity in epithelioid sarcoma and rhabdoid tumor by growth factor receptor modulation

BACKGROUND: Epithelioid sarcomas and rhabdoid tumors are rare, aggressive malignancies with poor prognosis. Both are characterized by INI1 alterations and deregulation of growth factor receptors albeit their interaction has not been elucidated. METHODS: In this study, we investigated the activity of...

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Detalles Bibliográficos
Autores principales: Harttrampf, Anne Catherine, da Costa, Maria Eugenia Marques, Renoult, Aline, Daudigeos-Dubus, Estelle, Geoerger, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290558/
https://www.ncbi.nlm.nih.gov/pubmed/34281526
http://dx.doi.org/10.1186/s12885-021-08579-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290558/
https://www.ncbi.nlm.nih.gov/pubmed/34281526
http://dx.doi.org/10.1186/s12885-021-08579-w

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