Transcutaneous penetration of a single-chain variable fragment (scFv) compared to a full-size antibody: potential tool for atopic dermatitis (AD) treatment

Currently, several biologics are used for the treatment of cutaneous pathologies such as atopic dermatitis (AD), psoriasis or skin cancers. The main administration routes are subcutaneous and intravenous injections. However, little is known about antibody penetration through the skin. The aim was to...

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Detalles Bibliográficos
Autores principales: Baylet, Audrey, Vyumvuhore, Raoul, Laclaverie, Marine, Marchand, Laëtitia, Mainzer, Carine, Bordes, Sylvie, Closs-Gonthier, Brigitte, Delpy, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290589/
https://www.ncbi.nlm.nih.gov/pubmed/34281610
http://dx.doi.org/10.1186/s13223-021-00574-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290589/
https://www.ncbi.nlm.nih.gov/pubmed/34281610
http://dx.doi.org/10.1186/s13223-021-00574-x

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