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Transcutaneous penetration of a single-chain variable fragment (scFv) compared to a full-size antibody: potential tool for atopic dermatitis (AD) treatment
Currently, several biologics are used for the treatment of cutaneous pathologies such as atopic dermatitis (AD), psoriasis or skin cancers. The main administration routes are subcutaneous and intravenous injections. However, little is known about antibody penetration through the skin. The aim was to...
Autores principales: | Baylet, Audrey, Vyumvuhore, Raoul, Laclaverie, Marine, Marchand, Laëtitia, Mainzer, Carine, Bordes, Sylvie, Closs-Gonthier, Brigitte, Delpy, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290589/ https://www.ncbi.nlm.nih.gov/pubmed/34281610 http://dx.doi.org/10.1186/s13223-021-00574-x |
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