Lentiviral CRISPR-guided RNA library screening identified Adam17 as an upstream negative regulator of Procr in mammary epithelium

BACKGROUND: Protein C receptor (Procr) has recently been shown to mark resident adult stem cells in the mammary gland, vascular system, and pancreatic islets. More so, high Procr expression was also detected and used as indicator for subsets of triple-negative breast cancers (TNBCs). Previous study...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Ting, Wang, Yinghua, Xiao, Tianxiong, Ai, Yirui, Li, Jinsong, Zeng, Yi Arial, Yu, Qing Cissy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290623/
https://www.ncbi.nlm.nih.gov/pubmed/34281556
http://dx.doi.org/10.1186/s12896-021-00703-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290623/
https://www.ncbi.nlm.nih.gov/pubmed/34281556
http://dx.doi.org/10.1186/s12896-021-00703-9

Ejemplares similares