TNF stimulation primarily modulates transcriptional burst size of NF‐κB‐regulated genes

Cell‐to‐cell heterogeneity is a feature of the tumor necrosis factor (TNF)‐stimulated inflammatory response mediated by the transcription factor NF‐κB, motivating an exploration of the underlying sources of this noise. Here, we combined single‐transcript measurements with computational models to stu...

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Detalles Bibliográficos
Autores principales: Bass, Victor L, Wong, Victor C, Bullock, M Elise, Gaudet, Suzanne, Miller‐Jensen, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290835/
https://www.ncbi.nlm.nih.gov/pubmed/34288498
http://dx.doi.org/10.15252/msb.202010127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8290835/
https://www.ncbi.nlm.nih.gov/pubmed/34288498
http://dx.doi.org/10.15252/msb.202010127

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